(figure presented) (5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ols were synthesized by three-component reactions of 1H-1,2,4-triazol-3-amine with aromatic aldehydes and acetone in the presence of TsOH. Antimicrobial and antifungal activities of these new substances were investigated in vitro.
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- Biological activity
- Microwave-assisted synthesis
- Molecular structure investigation
- Multicomponent reactions