(5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-ols as products of three-component condensation

Sergey A. Komykhov, Andrey A. Bondarenko, Vladimir I. Musatov, Mikhail V. Diachkov, Nikolay Yu Gorobets, Sergey M. Desenko

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


(figure presented) (5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ols were synthesized by three-component reactions of 1H-1,2,4-triazol-3-amine with aromatic aldehydes and acetone in the presence of TsOH. Antimicrobial and antifungal activities of these new substances were investigated in vitro.

Original languageEnglish
Pages (from-to)378-380
Number of pages3
JournalChemistry of Heterocyclic Compounds
Issue number3
StatePublished - 1 Mar 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 Springer Science+Business Media New York.


  • 1H-1,2,4-triazol-3-amine
  • Biological activity
  • Microwave-assisted synthesis
  • Molecular structure investigation
  • Multicomponent reactions


Dive into the research topics of '(5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-ols as products of three-component condensation'. Together they form a unique fingerprint.

Cite this