TY - JOUR
T1 - (5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-ols as products of three-component condensation
AU - Komykhov, Sergey A.
AU - Bondarenko, Andrey A.
AU - Musatov, Vladimir I.
AU - Diachkov, Mikhail V.
AU - Gorobets, Nikolay Yu
AU - Desenko, Sergey M.
N1 - Publisher Copyright:
© 2017 Springer Science+Business Media New York.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - (figure presented) (5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ols were synthesized by three-component reactions of 1H-1,2,4-triazol-3-amine with aromatic aldehydes and acetone in the presence of TsOH. Antimicrobial and antifungal activities of these new substances were investigated in vitro.
AB - (figure presented) (5S,7R)-5-Aryl-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ols were synthesized by three-component reactions of 1H-1,2,4-triazol-3-amine with aromatic aldehydes and acetone in the presence of TsOH. Antimicrobial and antifungal activities of these new substances were investigated in vitro.
KW - 1H-1,2,4-triazol-3-amine
KW - Biological activity
KW - Microwave-assisted synthesis
KW - Molecular structure investigation
KW - Multicomponent reactions
UR - http://www.scopus.com/inward/record.url?scp=85018800144&partnerID=8YFLogxK
U2 - 10.1007/s10593-017-2059-z
DO - 10.1007/s10593-017-2059-z
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:85018800144
SN - 0009-3122
VL - 53
SP - 378
EP - 380
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
IS - 3
ER -