Personal profile

About Me

I received my academic training at Tel Aviv University in the laboratory of Prof. Eugene Rosenberg where I was trained as a microbial ecologist and a classical microbiologist. After finishing my PhD, moved to Cornell for postdoctoral training in the laboratory of Dr. Ruth Ley. During my postdoc I was part of the NIH Human Microbiome Project (HMP) and also studied the how pregnancy influences the microbiota (resulted in a publication in Cell 2012). My postdoc resulted in more than 25 publications, some of which were collaborations with leading scientists in the field. As part of the HMP I helped create pipelines for data analysis and developed tools for the analysis of “big data” and also analyzed the data for the paper that appeared in Nature 2012. After 3.5 years I returned to Israel (2013) and set up my lab at the newly established med school of Bar Ilan University. In my lab we study the interaction between the microbiome and the endocrine system and the effects on behavior.

Numerous studies have shown that the microbial composition changes throughout healthy development and in various disease states. Our research focuses on the two major questions in this field relating to the dual interactions between microbiota and the host: how do the bacteria affect the host, and how does the host affect the bacteria?
Among our main interests are the interactions between the microbiome and the host endocrine system. A good example of this is in pregnancy, during which significant changes in microbiota composition, host hormonal levels, and immune responsiveness all converge to attain healthy fetal development. Another interest in our lab includes the affects of the microbiome on host social behavior.
Our methods are varied and include next generation sequencing (NGS), computational analysis, and fecal transplants. We believe that beyond a better understanding of the healthy microbiota composition and its interactions with the host, results of our studies may lead to development of therapies such as specific probiotics to ameliorate disease states.

Teaching:
Microbiology

Research Area:
The Microbiome in Health and Disease

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 6 - Clean Water and Sanitation
  • SDG 13 - Climate Action
  • SDG 14 - Life Below Water

Education/Academic qualification

PhD, Tel Aviv University

Oct 2003Oct 2007

Award Date: 1 Oct 2007

Master's Degree, Tel Aviv University

Oct 2001Jun 2003

Award Date: 1 Jun 2003

Bachelor

Oct 1998Jun 2001

Award Date: 1 Jun 2001

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Collaborations and top research areas from the last five years

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  • Antibiotic-perturbed microbiota and the role of probiotics

    Szajewska, H., Scott, K. P., de Meij, T., Forslund-Startceva, S. K., Knight, R., Koren, O., Little, P., Johnston, B. C., Łukasik, J., Suez, J., Tancredi, D. J. & Sanders, M. E., Mar 2025, In: Nature Reviews Gastroenterology and Hepatology. e043054.

    Research output: Contribution to journalReview articlepeer-review

    2 Scopus citations
  • Association of Adult Atopic Dermatitis with Impaired Oral Health and Oral Dysbiosis: A Case-Control Study

    Shahin, A., Leshem, Y. A., Taieb, Y., Baum, S., Barzilai, A., Jeddah, D., Sharon, E., Koren, O., Tzach-Nahman, R., Coppenhagen-Glazer, S., Hazan, R., Houri-Haddad, Y. & Greenberger, S., Feb 2025, In: International Dental Journal. 75, 1, p. 279-287 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • From big data and experimental models to clinical trials: Iterative strategies in microbiome research

    Turjeman, S., Rozera, T., Elinav, E., Ianiro, G. & Koren, O., 6 Mar 2025, In: Cell. 188, 5, p. 1178-1197 20 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • International consensus statement on microbiome testing in clinical practice

    Porcari, S., Mullish, B. H., Asnicar, F., Ng, S. C., Zhao, L., Hansen, R., O'Toole, P. W., Raes, J., Hold, G., Putignani, L., Hvas, C. L., Zeller, G., Koren, O., Tun, H., Valles-Colomer, M., Collado, M. C., Fischer, M., Allegretti, J., Iqbal, T. & Chassaing, B. & 49 others, Keller, J., Baunwall, S. M., Abreu, M., Barbara, G., Zhang, F., Ponziani, F. R., Costello, S. P., Paramsothy, S., Kao, D., Kelly, C., Kupcinskas, J., Youngster, I., Franceschi, F., Khanna, S., Vehreschild, M., Link, A., De Maio, F., Pasolli, E., Miguez, A. B., Brigidi, P., Posteraro, B., Scaldaferri, F., Stojanovic, M. R., Megraud, F., Malfertheiner, P., Masucci, L., Arumugam, M., Kaakoush, N., Segal, E., Bajaj, J., Leong, R., Cryan, J., Weersma, R. K., Knight, R., Guarner, F., Shanahan, F., Cani, P. D., Elinav, E., Sanguinetti, M., de Vos, W. M., El-Omar, E., Dorè, J., Marchesi, J., Tilg, H., Sokol, H., Segata, N., Cammarota, G., Gasbarrini, A. & Ianiro, G., Feb 2025, In: The Lancet Gastroenterology and Hepatology. 10, 2, p. 154-167 14 p.

    Research output: Contribution to journalReview articlepeer-review

    5 Scopus citations
  • Microbes Saving Lives and Reducing Suffering

    Timmis, K., Karahan, Z. C., Ramos, J. L., Koren, O., Pérez-Cobas, A. E., Steward, K., de Lorenzo, V., Caselli, E., Douglas, M., Schwab, C., Rivero, V., Giraldo, R., Garmendia, J., Turner, R. J., Perlmutter, J., Borrero de Acuña, J. M., Nikel, P. I., Bonnet, J., Sessitsch, A. & Timmis, J. K. & 7 others, Pruzzo, C., Prieto, M. A., Isazadeh, S., Huang, W. E., Clarke, G., Ercolini, D. & Häggblom, M., Jan 2025, In: Microbial Biotechnology. 18, 1, e70068.

    Research output: Contribution to journalEditorial

    Open Access
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