20012024

Research activity per year

Personal profile

About Me

I completed my PhD at the Structural Biology Department at the Weizmann Institute and conducted my post-doctoral studies at the NIH under supervision of Dr. Adriaan Bax. My research interests are the structure, dynamics, function and interactions of proteins in the biological contexts of health and disease. Our main tool is structural NMR which is a powerful method for understanding the molecular basis of protein function. Specific interests include membrane proteins, intrinsically disordered proteins, and protein-protein interactions in a variety of biological systems. In our work we also combine complementary biophysical methods such as circular dichroism, isothermal titration calorimetry, sedimentation equilibrium, microscale thermophoresis and others. We have several ongoing collaborations with chemists and biologists in Israel and abroad. On the personal level, I am married (1992) with three children and my hobbies include chess, music (piano playing) and calendars.
 
Research
  • The KcsA potassium channel - structural basis for channel inhibition by toxins
  • Intrinsically disordered proteins, methods for their study by NMR
  • Protein-protein interactions affecting the cytoskeleton and actin polymerization
  • Membrane spanning peptides – how viral invasion of the membrane occurs.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Weizmann Institute of Science

Jan 1998Mar 2004

Award Date: 1 Mar 2004

Master's Degree

Oct 1994Jul 1998

Award Date: 1 Jul 1998

Bachelor

Oct 1988Jul 1991

Award Date: 1 Jul 1991

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Collaborations and top research areas from the last five years

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