Personal profile
About Me
Prof. Itay Onn is Associate Professor and Head of Infrastructure and Research Dept. His research focuses on higher-order genome organization and its impact on growth, development, and disease.
Personal Biographical Information:
I was born and raised in Givatayim, Israel. I served 5 years as a solider and an officer in a special combat engineers unit of the IDF. I earned my Ph.D. from the Hebrew University, and I continued to a post-doctoral training in the USA. In 2011 I joined a Senior Lecturer to the newly established Faculty of Medicine in the Galilee. I am married to Karin and a father to 3 children. I live in the Michmanim, a Mizpe on the top of the Kamon Mountain in the lower Galilee.
Research
Higher-order genome organization and its impact on growth, development, and disease.
OnnLab:
We study the mechanisms by which Structural Maintenance of Chromosome (SMC) protein complexes shape the three-dimensional structure of chromatin, and how mutations in their encoding genes are associated with human diseases.
- Chromosomal Dynamics and Instability
- Spatial Organization of the Chromatin
Education/Academic qualification
PhD, Hebrew University of Jerusalem
Jan 1997 → Jan 2004
Award Date: 1 Jan 2004
Master's Degree, Hebrew University of Jerusalem
Oct 1995 → Oct 1997
Award Date: 1 Oct 1997
Bachelor, Hebrew University of Jerusalem
Oct 1992 → Oct 1995
Award Date: 1 Oct 1995
Research
- Fields of Interest
- Chromosomal Dynamics and Instability
- Spatial Organization of Chromatin
- Higher-order genome organization and its impact on growth, development, and disease
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Developing a peptide to disrupt cohesin head domain interactions
Elias, M., Gani, S., Lerner, Y., Yamin, K., Tor, C., Patel, A., Matityahu, A., Dessau, M., Qvit, N. & Onn, I., 15 Sep 2023, In: iScience. 26, 9, 107498.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
UMSBP2 is chromatin remodeler that functions in regulation of gene expression and suppression of antigenic variation in trypanosomes
Soni, A., Klebanov-Akopyan, O., Erben, E., Plaschkes, I., Benyamini, H., Mitesser, V., Harel, A., Yamin, K., Onn, I. & Shlomai, J., 23 Jun 2023, In: Nucleic Acids Research. 51, 11, p. 5678-5698 21 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Disrupting the MAD2L2-Rev1 Complex Enhances Cell Death upon DNA Damage
Pernicone, N., Elias, M., Onn, I., Tobi, D. & Listovsky, T., 19 Jan 2022, In: Molecules. 27, 3, 636.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Fold-change of chromatin condensation in yeast is a conserved property
Yamin, K., Bijlani, S., Berman, J., Soni, A., Shlomai, J., Buragohain, B. M., Werbner, M., Gal-Tanamy, M., Matityahu, A. & Onn, I., 17 Oct 2022, In: Scientific Reports. 12, 1, 17393.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
It’s all in the numbers: Cohesin stoichiometry
Matityahu, A. & Onn, I., 18 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 1010894.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations
Prizes
Activities
-
SMC proteins
On, I. (Participation - Conference participant)
13 Jun 2017 → 16 Jun 2017Activity: Participating in or organizing an event › Organizing a conference, workshop, ...
-
Israeli Society of Genetics (External organization)
On, I. (Member)
2016 → …Activity: Membership › Membership of association
-
FASEB Yeast chromosomes
On, I. (Participation - Conference participant)
31 Jul 2016 → 5 Aug 2016Activity: Participating in or organizing an event › Organizing a conference, workshop, ...
Thesis
-
Chromosome instability of yeast artificial chromosome in S. cerevisae
On, I. (Author), Simchen, G. (Supervisor), 1997Student thesis: Thesis
-
Structure-function relationship of the C2H2 zinc finger protein UMSBP
On, I. (Author), Shlomay, Y. (Supervisor) & Margalit, H. (Supervisor), 2004Student thesis: Doctoral Thesis