Personal profile
About Me
Galit Shohat-Ophir is a researcher at the Faculty of Life Science and The Multidisciplinary Brain Research Center at Bar Ilan University. She received her PhD in Biochemistry from the Weizmann Institute of Science and continued for postdoctoral studies at University of California San-Francisco and HHMI Janelia Research Center. Her postdoctoral study was published in Science and received large public coverage including being on the front page of the New-York Times. She joined the Faculty of Life Science at Bar Ilan in 2013 and continued her research on the Molecular Basis of Social Interaction. Her research aims to uncover the molecular and neural mechanisms by which rewarding and stress related experiences are perceived, represented in the brain and converted into modulation of behavior, using a combination of cell specific transcriptome analysis, state of the art neurogenetic tools and novel tracking and machine vision technologies.
Animals execute many different behaviors in the course of their lives with the goal of surviving and reproducing; they find food and mates, defend themselves and in many cases care for their offspring or other relatives. When these behaviors involve the interaction with other members of the same species they are considered social interaction. Living in a social environment requires perception of a socially relevant sensory stimulus, representation of this information in the brain, and integration of the stimulus with other relevant cues. Thus, social experiences can induce long-lasting changes in neural circuit function and ultimately altered behavior.
My research interest is to define the principles by which social interactions among individuals produce specific changes in the brain that lead to modification of behavior. In particular I am interested in identifying the molecular signature of social experience within defined subset of neuronal populations. We are exploring this question using reproductive behavior, possibly the most important event in an animal’s life, using Drosophila melanogaster as a model system.
Education/Academic qualification
PhD, Weizmann Institute of Science
… → Jan 2006
Award Date: 1 Jan 2006
Bachelor, Ben-Gurion University of the Negev
… → Feb 2013
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Collaborations and top research areas from the last five years
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A highly conserved A-to-I RNA editing event within the glutamate-gated chloride channel GluClα is necessary for olfactory-based behaviors in Drosophila
Zak, H., Rozenfeld, E., Levi, M., Deng, P., Gorelick, D., Pozeilov, H., Israel, S., Paas, Y., Billy Li, J., Parnas, M. & Shohat-Ophir, G., 6 Sep 2024, In: Science advances. 10, 36, eadi9101.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons
Ryvkin, J., Omesi, L., Kim, Y. K., Levi, M., Pozeilov, H., Barak-Buchris, L., Agranovich, B., Abramovich, I., Gottlieb, E., Jacob, A., Nässel, D. R., Heberlein, U. & Shohat-Ophir, G., 18 Jan 2024, In: PLoS Genetics. 20, 1, 1011054.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
From promoter motif to cardiac function: a single DPE motif affects transcription regulation and organ function in vivo
Sloutskin, A., Itzhak, D., Vogler, G., Pozeilov, H., Ideses, D., Alter, H., Adato, O., Shachar, H., Doniger, T., Shohat-Ophir, G., Frasch, M., Bodmer, R., Duttke, S. H. & Juven-Gershon, T., 15 Jul 2024, In: Development (Cambridge). 151, 14, 56 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Courtship Conditioning/Suppression Assays in Drosophila
von Philipsborn, A. C., Shohat-Ophir, G. & Rezaval, C., 5 Jul 2023, In: Cold Spring Harbor Protocols. 2023, 7, p. 459-466 8 p.Research output: Contribution to journal › Article › peer-review
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Elevated A-to-I RNA editing in COVID-19 infected individuals
Merdler-Rabinowicz, R., Gorelik, D., Park, J., Meydan, C., Foox, J., Karmon, M., Roth, H. S., Cohen-Fultheim, R., Shohat-Ophir, G., Eisenberg, E., Ruppin, E., Mason, C. E. & Levanon, E. Y., 1 Dec 2023, In: NAR Genomics and Bioinformatics. 5, 4, 11 p., lqad092.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Prizes
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Recipient of the Sandler distinction fellowship for postdoctoral training award
Ophir, G. (Recipient), 2009
Prize
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Conference Invited
Ophir, G. (Invited speaker)
1 Jan 2018Activity: Talk or presentation › Invited talk
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Conference Invited
Ophir, G. (Invited speaker)
1 Sep 2018 → 14 Sep 2018Activity: Talk or presentation › Invited talk
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Conference Invited
Ophir, G. (Invited speaker)
1 Jan 2017Activity: Talk or presentation › Invited talk
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Conference Invited
Ophir, G. (Invited speaker)
1 Jan 2017Activity: Talk or presentation › Invited talk
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Conference Invited
Ophir, G. (Invited speaker)
1 Jan 2017Activity: Talk or presentation › Invited talk
Profiles
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Noa Avrech
- Bar-Ilan University - Faculty of Life Sciences, The Mina and Everard Goodman Faculty of Life Sciences - at Bar-Ilan University - MA Research Student
Person: Teaching, MA Research Student
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Hadar Pozeilov
- Bar-Ilan University - Interdisciplinary Studies Unit, Interdisciplinary Brain Science Program - PhD Student
- Bar-Ilan University - Faculty of Life Sciences, The Mina and Everard Goodman Faculty of Life Sciences - at Bar-Ilan University - PhD Student
Person: Teaching, PhD Student