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  • Tzafon Medical Center, Research Institute, Building No. 26

20112026

Research activity per year

Personal profile

About Me

Prof. Avi Peretz, teaches in the BIU Faculty of Medicine and is the Director of the Academia, Innovation and Research System (AIR) at the Tzafon Medical Center.

Research:

Infectious diseases are one of the most common causes of death worldwide. Among the reasons for this we can list the increase in the resistance  rate  of bacteria to antibiotics, alongside a sharp peak in the rate of hospital acquired infections. One of the challenges in the field is to identify the disease cause (bacterium, virus, parasite or fungus) quickly using various diagnostic tools, and to choose the appropriate treatment, for example, antibiotics.

As part of its activities the laboratory researches the virulence mechanisms of various bacteria, such as the ability to form biofilm, toxins that cause various damages, as well as the response of the immune system and the relationship between the pathogen and the host. The laboratory closely collaborates with various research laboratories around the world and in Israel, and takes part in important multi-center international studies. Many of the studies conducted in the laboratory include the use of clinical samples collected from patients with various infectious diseases, as well as the use of animal models and cell cultures.

In recent years, the laboratory focuses on the research of on Helicobacter pylori and Clostridioides difficile, and holds the largest bacterial bank in Israel.

Research

  • Fields of Interest
  • Microbiology
  • Bacterial virulence factors
  • Diagnostic microbiology and rapid diagnosis of infections
  • Hospital-acquired infections
  • Host–pathogen interaction

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Essential laboratory tests in emergencies; on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Committee on Preparation of Laboratories for Emergencies (C-PLE)

    Lippi, G., Alkhazashvili, M., Banuls Laetitia, M. Y., Cadamuro, J., Danese, E., De Guadiana Romualdo, L. G., Delacour, H., Favaloro, E. J., Favresse, J., Henry, B. M., Jovičić, S., Kütt, M., Ozben, T., Peoc’h, K., Peretz, A., Perović, A., Quaresima, V., Thachil, J., Yucel, D. & Plebani, M., 6 May 2026, (E-pub ahead of print) In: Clinical Chemistry and Laboratory Medicine.

    Research output: Contribution to journalArticlepeer-review

  • Genomic determinants of antibiotic resistance for Helicobacter pylori treatment: a retrospective phenotypic and genotypic observational study

    Martínez-Martínez, F. J., Chiner-Oms, Á., Furió, V., Martínez, F., Furió, V., Comas, I., Chiner-Oms, Á., Yamaoka, Y., Dekker, J. P., Megraud, F., Jauvain, M., Varon, C., Lehours, P., Jehanne, Q., Bénéjat, L., Ducournau, A., Romero-Gallo, J., Krishna, U., Peek, R. M. & Piazuelo, M. B. & 266 others, Wilson, K. T., Loh, J. T., Cover, T. L., Vale, F. F., Raaf, N., Aftab, H., Akada, J., Matsumoto, T., Haesebrouck, F., Bartelli, T. F., Nunes, D. N., Pelosof, A., Sztokfisz, C. Z., Dias-Neto, E., Assumpção, P. P., Karagyozov, P., Tishkov, I., Goodman, K. J., Geary, J., Cromarty, T. J., Price, N. L., Quilty, D., Corvalan, A. H., Gonzalez, R., Riquelme, A., García-Cancino, A., Parra-Sepúlveda, C., Castillo, F., Bravo, M. M., Pazos, A., Bravo, L. E., Fox, J. G., Ramírez-Mayorga, V., Molina-Castro, S., Durán-Bermúdez, S., Campos-Núñez, C., Chaves-Cervantes, M., Tshibangu-Kabamba, E., Tumba, G. D., Tshimpi-Wola, A., de Jesus Ngoma-Kisoko, P., Tshibangu, F. M., Mukanya, A. C., Nkomba, T. K., Cruz, M., Abreu, J. J., Secka, O., Link, A., Malfertheiner, P., Adinortey, M. B., Bockarie, A. S., Adinortey, C. A., Ofori, E. G., Sgouras, D. N., Martinez-Gonzalez, B., Michopoulos, S., Georgopoulos, S., Hernandez, E., Dominguez, R. L., Morgan, D. R., Harðardóttir, H., Gunnarsdóttir, A. I., Guðjónsson, H., Jónasson, J. G., Björnsson, E. S., Ballal, M., Shetty, V., Miftahussurur, M., Sugihartono, T., Alfaray, R. I., Waskito, L. A., Fauzia, K. A., Syam, A. F., Maulahela, H., Malekzadeh, R., Peretz, A., Azrad, M., On, A., De Re, V., Zanussi, S., Cannizzaro, R., Canzonieri, V., Shimura, T., Tokunaga, K., Osaki, T., Kamiya, S., Jadallah, K., Matalka, I., Igissin, N. S., Moldobaeva, M. S., Rakhat, A., Choi, I. J., Kim, J. G., Kim, N., Leja, M., Vangravs, R., Šķenders, Ģ., Rūdule, A., Kikuste, I., Vanags, A., Rudzīte, D., Kupcinskas, J., Kiudeliene, E., Kiudelis, V., Gedgaudas, R., Jonaitis, P., Kiudelis, G., Jonaitis, L., Skieceviciene, J., Vadivelu, J., Loke, M. F., Vellasamy, K. M., Herrera-Goepfert, R., Alonso-Larraga, J. O., Yee, T. T., Htet, K., Matsuhisa, T., Shrestha, P. K., Ansari, S., Abiodun, O., Jemilohun, C., Akande, K. O., Olu-Abiodun, O., Magaji, F. A., Omotoso, A., Okonkwo, U., Osuagwu, C. C., Owoseni, O. O., Castaneda, C., Castillo, M., Velapatino, B., Gilman, R. H., Krzyżek, P., Gościniak, G., Pawełka, D., Korona-Glowniak, I., Cichoz-Lach, H., Oleastro, M., Figueiredo, C., Machado, J. C., Ferreira, R. M., Bordin, D. S., Livzan, M. A., Tsukanov, V. V., Tan, P., Yeoh, K. G., Zhu, F., Ally, R., Haas, R., Fischer, W., Montes, M., Fernández-Reyes, M., Tamayo, E., Lizasoain, J., Bujanda, L., Lario, S., Ramírez-Lázaro, M. J., Calvet, X., Brunet-Mas, E., Domper-Arnal, M. J., García-Mateo, S., Abad-Baroja, D., Delgado-Guillena, P., Moreira, L., Botargues, J., Pérez-Martínez, I., Barreiro-Alonso, E., Flores, V., Gisbert, J. P., Muro, E. A., Linares, P., Alcoba, L., Martin, V., Engstrand, L., Enroth, H., Keller, P. M., Wagner, K., Pohl, D., Lee, Y. C., Liou, J. M., Wu, M. S., Kocazeybek, B., Sarıbas, S., Tasçı, İ., Demiryas, S., Kepil, N., Quiel, L., Villagra, M., Norton, M., Johnson, D., Huang, R. J., Hwang, J. H., Szymczak, W., Jacobs, W. R., In, H., Bollag, R., Lopez, A., Kruse, E. J., White, J., Lane, C., Gao, Y., Gold, B. D., Cruz-Correa, M., González-Pons, M., Rodriguez, L. M., Tuan, V. P., Quy Dung, H. D., Binh, T. T., Huyen Trang, T. T., Van Khien, V., Katsura, Y., Gonzalez-Hormazabal, P., Tarazona-Santos, E., Zamudio, R., Mariño-Ramírez, L., Backert, S., Naumann, M., Smet, A., Berg, D. E., Yahara, K., Blaser, M. J., Vincze, T., Morgan, R. D., Roberts, R. J., Torres, J., Torres, R. C., Noureen, M., Cherry, J. L., Osada, N., Fukuyo, M., Arita, M., Sandoval-Motta, S., Agostini, R. B., Ghirotto, S., Muñoz-Ramírez, Z. Y., Falush, D., Thorell, K., Uchiyama, I., Kobayashi, I., Wang, D., Hicks, B., Yeager, M., Hutchinson, A., Teshome, K., Jones, K., Luo, W., Goldstein, A. M., Hu, N., Taylor, P. R., Song, M., Yu, K., Zhu, B., Abnet, C. C., Rabkin, C. S., Camargo, M. C., Yamaoka, Y., Dekker, J. P., Mégraud, F., Bénéjat, L., Ducournau, A., Giese, A., Jehanne, Q., Jauvain, M., Camargo, M. C., Comas, I. & Lehours, P., Jan 2026, In: The Lancet Microbe. 7, 1, 101217.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Probiotics Ameliorate Histological Alterations and Prevent Increases in Cytokine and Toxin Levels in Mice Infected with Various Clostridioides difficile Strains

    Hamo, Z., Ninio, H., Azrad, M., Binyamin, D., Zigdon, M., Roshrosh, H. & Peretz, A., Mar 2026, In: Probiotics and Antimicrobial Proteins. 18, 2, p. 1765-1774 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Diagnosing gastrointestinal infections based on cycle threshold cut-offs of PCR

    Karam, R., Kechker, P., Ken-Dror, S., Peretz, A. & Azrad, M., 4 Feb 2025, In: Microbiology spectrum. 13, 2

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Editorial: Innovation in tackling the global challenge of eradicating antibiotic-resistant microorganisms

    Nissan, I. & Peretz, A., 2025, In: Frontiers in Microbiology. 16, 1774105.

    Research output: Contribution to journalEditorial

    Open Access