Personal profile
About Me
Associate professor at the Azrieli Faculty of Medicine. Ph.D. in Genetics from the Hebrew University of Jerusalem. Postdoctoral studies at the University of California, San Diego. Research interests include the structure and function of the cell nucleus, with an emphasis on the Nuclear Pore Complex (NPC) and a group of human diseases known as nuclear envelopathies. The NPC serves as a portal for the selective exchange of macromolecules between the nucleus and cytoplasm.
Research Area
- Nuclear Structure & Function
Laboratory
Prof. Amnon Harel is Head of International Study Programs and head of the Nuclear Structure and Function Lab.
Research in the laboratory focuses on the molecular mechanisms underlying NPC biogenesis, the translocation of different cargoes through the central pore channel and developing new techniques for imaging various cellular structures by scanning electron microscopy. Recent work in Prof. Harel's lab has revealed specific mutations in human nuclear envelope and NPC components that cause severe neurodegenerative conditions.
Education/Academic qualification
PhD, Hebrew University of Jerusalem
Jan 1989 → Jan 1997
Award Date: 1 Jan 1997
Bachelor, Hebrew University of Jerusalem
Oct 1985 → Oct 1988
Award Date: 1 Oct 1988
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae
Piscon, B., Fichtman, B., Harel, A., Adler, A., Rahav, G. & Gal-Mor, O., 2025, In: Frontiers in Cellular and Infection Microbiology. 15, 1550545.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A single filament biomechanical study of the enteropathogenic Escherichia coli Type III secretion system reveals a high elastic aspect ratio
Elias-Mordechai, M., David, N., Oren, S., Georgia Pelah, M., Jopp, J., Fichtman, B., Harel, A., Berkovich, R. & Sal-Man, N., 21 Sep 2023, In: Nanoscale. 15, 36, p. 15027-15037 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
The Effect of Outer Space and Other Environmental Cues on Bacterial Conjugation
Piscon, B., Esposito, E. P., Fichtman, B., Samburski, G., Efremushkin, L., Amselem, S., Harel, A., Rahav, G., Zarrilli, R. & Gal-Mor, O., 15 Jun 2023, In: Microbiology spectrum. 11, 3Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The magnified view: from ancient trinkets to single nuclear pore complexes
Fichtman, B. & Harel, A., Oct 2023, In: FEBS Letters. 597, 20, p. 2590-2596 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
UMSBP2 is chromatin remodeler that functions in regulation of gene expression and suppression of antigenic variation in trypanosomes
Soni, A., Klebanov-Akopyan, O., Erben, E., Plaschkes, I., Benyamini, H., Mitesser, V., Harel, A., Yamin, K., Onn, I. & Shlomai, J., 23 Jun 2023, In: Nucleic Acids Research. 51, 11, p. 5678-5698 21 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Prizes
Activities
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Conference Invited
Harel, A. (Invited speaker)
1 Feb 2020Activity: Talk or presentation › Invited talk
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Conference Invited
Harel, A. (Invited speaker)
1 Aug 2019 → 6 Aug 2019Activity: Talk or presentation › Invited talk
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Departmental Seminar/Colloquium: A tale of two envelopathies; Or: How I learned to stop worrying and love translational research
Harel, A. (Keynote speaker)
2019 → …Activity: Talk or presentation › Oral presentation
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The American Society of Human Genetics (External organization)
Harel, A. (Member)
2019 → …Activity: Membership › Membership of association
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Conference Invited
Harel, A. (Invited speaker)
1 Jul 2018 → 5 Jul 2018Activity: Talk or presentation › Invited talk